International group of scientists for the first time were able to identify the biological mechanism underlying the therapeutic effect of deep meditation. The researchers found that as a result of all eight hours of meditation in the body are the specific changes at the genetic and molecular level. The work is published in the journal Psychoneurosis. Authors-specialists from the University of Wisconsin (United States), the Institute of biomedical research (Barcelona, Spain) and the Center for neurological Research Institute (Lyon, France), studied the effect of a day out in clear mind meditation on a group of 19 experienced mediators.
Clear mind Meditation-the State Fair awareness of what is happening. In this form of human meditation guide focusing on your breath and bodily sensations, quietly flowing through the uncomfortable thoughts and emotions. In the control group was 21 a person with no experience of meditation. They were invited to engage in peaceful non-meditative exercises in the same environment.
All participants before and after the experiment were determined by levels of gene expression of rhythms, chromatin modification and reaction of inflammation in the mononuclear cells of peripheral blood. In addition, both groups were specific tests to evaluate indicators of stress resistance of the organism. At the start of the levels of expression of the genes for both groups were about the same.
However, as has been found in seven hours of deep meditation raised several histone deaconesses HDACS, genes that regulate the activity of other genes, and pro-inflammatory genes RIPK2 and COX2. All of these genes expression levels were the mediators are reduced compared to the control group. The downgrade RIPK2 genes and HDAC2, researchers found, due to the faster the physical rehabilitation of the body after the release of the hormone cortisol in stressful social situations-for example, when you need to ad lib to speak before the public.
The fact that the changes have not affected the remaining genes shows that meditation affects only some specific regulatory pathways involved in the mechanisms underlying its therapeutic potential, the authors note. There are Changes in the genes, which are usually the target of anti-inflammatory and analgesic drugs, so the results are the basis for future studies of meditative practices to therapy of chronic inflammatory diseases, the authors emphasize.